腸道微生物組研究發(fā)現(xiàn),速溶黑茶喂養(yǎng)的大鼠在門水平上顯著改變了腸道微生物種類。與HFD相比,高劑量速溶黑茶(HIDT)顯著提高了有益菌Akkermansia和Rikenellaceae_RC9的相對豐度,降低了有害菌Ruminococcaceae_UCG-005和Ruminiclostridium_9的相對豐度(p<0.01)。經(jīng)研究表明,Akkermansia菌已被廣泛認為與肥胖、糖尿病、炎癥和代謝紊亂顯著負相關(guān)。[1]口服巴氏滅活A(yù)kkermansia菌,可提高約30%的胰島素敏感性,降低胰島素血癥和血漿總膽固醇。[2]
該研究進一步為速溶黑茶調(diào)節(jié)糖脂代謝的功能提供了有效的分子依據(jù)。
來源:湖南茶業(yè),有改動,侵刪
參考文獻:
[1] Everard A , Belzer C , Geurts L , et al. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity[J]. Proceedings of the National Academy of Sciences of the United States of America, 2013, 110(22):9066-9071.
[2] Depommier C , Everard A , Druart C , et al. Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study[J]. Nature Medicine, 2019, 25(7):1096.